Aapptec Endeavor 90 Tabletop Peptide Synthesizer

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Aapptec Endeavor 90 Tabletop Peptide Synthesizer

Endeavor 90-III Peptide Synthesizer is a small laboratory size solid phase peptide instrument with production scale capacity.  It fits on a bench top and does not require a hood but can prepare up to 200 mmoles of peptide in a single synthesis without sacrificing quality. The Endeavor 90 is an ideal instrument for scaling up from research scale to mini-pilot production and developing production scale protocols.  The Endeavor 90-III solid phase peptide synthesizer is excellent for small scale GMP and GLP production of peptides for phase I and phase II studies.

Documentation

The Endeavor 90 III peptide synthesizer provides documentation backup of all functions to the hard drive, with simultaneous printing capabilities. All liquids are transferred through stainless steel, TFE tubing or glass. Calibration of delivery can also be confirmed to meet all regulations. The software and hardware allows for any type of chemistry, including Boc and Fmoc.

Easy to Use

The Endeavor 90 III peptide synthesizer has many features that make it easy to use. The control software is user-friendly, easy-to-learn and intuitive. Amino acid vessels are automatically washed after delivery of the amino acid making them ready to be filled with another amino acid. Optional UV-reaction monitoring for Fmoc protocols is available.

Production

The Endeavor 90 III peptide instrument is also a useful laboratory production tool, ideal for coupling linkers to core resins, preparing amino acid substituted resins or preparing specialized resins. The large 1L and optional 2L reactors can process up to 100 g of resin.

  • Vortex Mixing, Nitrogen bubbling or Both
  • Smart-Chem Software with Automated Synthesis and User-Friendly Setup
  • Affordable and Reliable with Low Solvent Consumption and Unlimited Flexibility

Endeavor 90 Brochure

Product Specifications

Width 25.25″ (64 cm)
Depth 14.75″ (37.5 cm)
Height 32″ (81 cm) including reagent bottles
Weight 80 lbs (37 kg)
Fluid Transfer Nitrogen pressure, regulated to 10 psi (Pa 68947)
Cycle Time
  • Organic: Depends on chemistry
  • Peptide: Approximately one to two hours for concurrent dual synthesis, 45 minutes for rapid, small-scale HBTU-activated single reactor runs
Control Microsoft Windows XP™
Standard Configuration
  • Endeavor 90 – (2) 25 mL reactant vessel
  • Endeavor 90-II – (1) Choice of any reactant vessel size
  • Optional RV Sizes: 5, 25, 50, 100, 200, 300, 500, 1L and 2L
  • Reactors above 100 mL are utilized in the single reactor configuration
  • Four 90 mL reactant vessels (250 mL optional for large scale synthesis)
  • Three 2L reagent bottles (5L+ standard for large-scale platforms)
  • Four 1L reagent bottles (2L+ standard for large-scale platforms)
  • Integrated deprotection/cleavage reagent system
Scale
  • Dual Reactor: 0.05 to 5 g resin (from 20 mg to 5-6 g crude product)
  • Single Reactor: Up to 35 g resin (approximately 30-35 g crude product) (optional 1L & 2L RV allows 50 g – 200 g resin)
Warranty One-year limited parts and labor